Boston

Former Research Setting

Boston, MA

Nghiem Lab

The Nghiem lab is composed of several research bays in the midst of an open laboratory environment, facilitating sharing of ideas and reagents among the twelve laboratories of the CBRC. Within or adjacent to this space is a microscopy suite, standard molecular biology facilities such as ultra centrifuges and cold room. Core facilities supported by the CBRC, and present on the third floor include transgenic animal core, histology core, fluorescence activated cell sorter core, protein synthesis/analysis core, and confocal microscopy core.

[back to top]

Cutaneous Biology Research Center

The CBRC consists of 12 Principal Investigators working on skin biology and basic biology relevant to skin. The CBRC was founded in 1989 through the support of the Shiseido Corporation of Japan, under the leadership of John Parrish, MD, the Harvard Medical School and Massachusetts General Hospital.

Link to CBRC Main Page.

[back to top]

Seminars

In addition, there are many ad hoc seminars that occur in the building on a daily basis.

[back to top]

Building 149, MGH-East

USS Constitution (Old Ironsides) on its annual 4th of July tour of Boston Harbor. The brown striped buildings in the background are Buildings 149 and 199 (parking). Photo courtesy of Satoshi Hirakawa, MD, PhD.

The Cutaneous Biology Research Center is located in the Lawrence E. Martin (LEM) Laboratories (Building 149) in the Charlestown section of the City of Boston on a 139 acre site of the former Charlestown Navy Yard. Building 149 is the largest structure in the original Navy Yard and has been home to a large biomedical research center since 1989. Major research efforts in Building 149 include dermatology, cancer, renal, medical imaging, neuroscience, infectious disease, cardiovascular research, radiation biology and immunology. The Navy Yard is approximately a 10-minute shuttle ride from the main campus of Massachusetts General Hospital (MGH), with shuttles running every 15 minutes through the day and evening.

view mapquest map of our location
view shuttle schedule

The interior of the building consists of 8 and 10-story sections with an aggregate of 649,815 square feet of usable space organized around two central atria, which extend from the ground floor to the roof. The designers utilized the atria by locating open laboratories along the building perimeter and centralizing the supporting offices, allowing natural light into the labs and office spaces while also creating efficient use of space. Each floor has two main entrances connected by extensive interior promenade. The promenade is granite and includes a fountain, interior landscaping and natural light from the atria. The larger atrium serves as a dining hall/cafeteria, with natural light and trees.

Building 149 was built according to plans approved by the U.S. Navy in 1917 and further expanded in 1918 and 1919 to its present 10-story structure. With the large open floor space (each of which is approximately 75,000 square feet), and high load capacity (up to 450 pounds/square foot), associated with its former warehouse use, Building 149 has been a most suitable structure for reconstruction into a modern research facility.

Building 149 is connected by four enclosed pedestrian bridges to an adjacent 9-story, 1400 space parking structure, Building 199. Together these buildings comprise a 1,260,000 square foot research, office, retail and parking complex.

Major goals of the research program at the Charlestown Navy Yard are 1) Enhances recruitment of leading research scientists of various disciplines by providing a state-of-the-art environment, both spatially and collegially. 2) Concentrates research programs that have significant monetary support allowing access to shared resources. 3) Allows broad cross fertilization of interdisciplinary programs on the same floors that would not have been possible at the main campus.

[back to top]

[back to Current Research Setting, Seattle, WA]